6th Sense Analytics
Raleigh, NC
CEO: Greg Burnell
Partner: Kip Frey
6th Sense Analytics' technology platform enables the measurement of software development efficiency and productivity, providing individual developers and development teams with performance data and benchmarks against which to measure software development activity and effectiveness.
Accipiter
Raleigh, NC
Partner: Mitch Mumma
Nasdaq: CMGI
Accipiter developd and marketed Internet application software enabling websites to deliver targeted advertising based on specific demographic profiles and to track individual visitors on a site. The company was acquired by CMG Information Services in 1998.
Accordant Health Services
Greensboro, NC
CEO: Steve Schelhammer
Partner: Dennis Dougherty
NYSE: CMX
Accordant is a disease management company with a special focus on individuals living with high impact, complex chronic diseases.
Aldagen
Durham, NC
CEO: Tom Amick
Partner: Garheng Kong
Aldagen is focused on regenerative medicine. The company's proprietary products identify and isolate unique populations of adult stem cells with the potential to revolutionize treatments of cardiovascular and other degenerative diseases.
Alimera Sciences Inc.
Atlanta, GA
CEO: Dan Myers
Partner: Phil Tracy
Alimera is a specialty pharmaceutical company specializing in the development and commercialization of ophthalmic products.
Applied Genetic Technologies Corp.
Alachua, FL
CEO: Sue Washer
Partner: Garheng Kong
AGTC is a gene therapy company that designs, packages and delivers therapeutic genes to treat medical illnesses using the adeno-associates virus.
Argolyn Bioscience
Charleston, SC
CEO: Pearce Gilbert
Partners: Dennis Dougherty, David Pierson
Argolyn Bioscience uses proprietary peptide modification methods to repeatedly derive and develop novel and value-added therapeutic products to address major unmet medical needs.
Argos Therapeutics
Research Triangle Park, NC
CEO: John Bonfiglio
Partner: Phil Tracy
Argos is an immunotherapy company dedicated to the treatment of metastatic cancers and chronic infectious diseases resistant to current therapies.
Athenix Corp.
Durham, NC
CEO: Mike Koziel
Partner: Dennis Dougherty
Athenix is a leading biotechnology company developing high-value, bio-industrial products for the agricultural and chemical industries using genetic traits from microbes.
Biolex Therapeutics
Pittsboro, NC
CEO: Jan Turek
Partners: Dennis Dougherty, Chris Hegele
Biolex is advancing its process for manufacturing proteins as human therapeutic drugs, manufacturing these proteins for pharmaceutical partners while also developing its own proteins using its proprietary system.
Bright Hub
Vienna, VA
CEO: Bill Phelan
Partner: Mitch Mumma
Bright Hub supports software developers working primarily with open source software by providing them with a business infrastructure to complement the development tools they employ in the Microsoft® Visual Studio environment.
Burl Software
Raleigh, NC
Partner: Mitch Mumma
Burl Software was a provider of the leading software tools for examining and repairing large legacy enterprise software systems. Burl was acquired by Micro Focus in 1995.
CallMiner
Fort Myers, FL
CEO: Terry Leahy
Partner: John Glushik
CallMiner develops speech analytics solutions that deliver near real-time customer intelligence from recorded conversations, enabling companies to discover why customers call and how agents respond.
Cellective Therapeutics
Gaithersburg, MD
Partner: Garheng Kong
Nasdaq: MEDI
Cellective was a biopharmaceutical company focused on developing industry-leading therapeutic antibodies for the treatment of oncology and immune-related diseases. The company was acquired by MedImmune in 2005.
Cempra Pharmaceuticals
Morrisville, NC
CEO: Prabha Fernandes
Partner: Garheng Kong
Cempra develops medicines to meet the increasing need for treating drug-resistant bacterial infections in the community and hospital. The company is focused on market opportunities in anti-infectives.
Clarabridge
Reston, VA
CEO: Sid Banerjee
Partner: John Glushik
Clarabridge's text-mining software enables customers to transform text into valuable information to improve market research, customer care, product development, quality assurance and risk management.
Comstock Systems Corporation
Mountain View, CA
Partner: Mitch Mumma
NYSE: HIT
Comstock is a developer of Internet infrastructure systems that enable vendors of digital media to optimize pricing and distribution. Comstock was acquired by Hitachi, Ltd. in 2002.
COVEGA Corporation
Jessup, MD
CEO: Joe Dixon
Partner: Chris Hegele
COVEGA is a leading provider of components and integrated-optic subsystems to the telecommunications, data communications, military and cable television industries. COVEGA merged with Gemfire in February 2008.
Covelight Systems
Cary, NC
Partner: Kip Frey
Nasdaq: RDWR
Covelight provides enterprise-class security solutions for companies that use online applications and Web services. The company was acquired by Radware in April 2007.
Digital Optics Corporation
Charlotte, NC
Partner: Mitch Mumma
Nasdaq: TSRA
Digital Optics develops, designs and manufactures wafer-based micro-optics. Tessera Technologies acquired DOC in July 2006.
Encelle, Inc.
Raleigh, NC
CEO: Jim Woodward
Partner: Chris Hegele
Encelle developed novel products for tissue regeneration. The company was acquired by Pioneer Surgical Technology in June 2007.
Extensibility™
Chapel Hill, NC
Partner: Mitch Mumma
Nasdaq: TIBX
Extensibility provides cutting-edge XML schema development, conversion and management solutions in order to facilitate the transition of traditional applications to the new order of Internet information systems. Extensibility was acquired by TIBCO Software, Inc.
HexaTech, Inc.
Raleigh, NC
Partner: John Glushik
HexaTech develops single crystal aluminum nitride substrates for electronic and optoelectronic semiconductor devices.
Icoria
Research Triangle Park, NC
Partner: Dennis Dougherty
Nasdaq: ICOR.PK
Icoria is an agricultural biotechnology company industrializing the process of gene function discovery for four major sectors of the global economy: human health, nutrition, crop production, and industrial products.
Infoglide Software Corporation
Austin, TX
CEO: Mike Shultz
Partner: Mitch Mumma
Infoglide provides enterprise software that enables organizations to unlock information stored in large and disparate databases, allowing for real-time analysis and comparisons across multiple databases without moving the data from secure locations.
Insmed Incorporated
Richmond, VA
Partner: Dennis Dougherty
Nasdaq: INSM
Insmed is focused on the development of drugs to treat metabolic and endocrine-related diseases and disorders associated with insulin resistance.
Inspire Pharmaceuticals
Durham, NC
Partner: Dennis Dougherty
Nasdaq: ISPH
Inspire is a pharmaceutical company discovering and developing new drugs to treat diseases characterized by deficiencies in the body’s innate defense mechanisms of mucosal hydration and mucociliary clearance.
Integrated Silicon Systems
Durham, NC
Partner: Dennis Dougherty
Nasdaq: SNPS
ISS develops software tools that automate and accelerate integrated circuit design. ISS was acquired by Synopsys, Inc.
Integrian
Research Triangle Park, NC
CEO: Pete Durand
Partner: John Glushik
Integrian provides ruggedized mobile digital video technology for the public safety and transit markets.
Invistics
Atlanta, GA
CEO: Scott Geller
Partner: Kip Frey
Invistics has developed manufacturing performance management software that helps pharmaceutical, industrial equipment and high tech companies accelerate factory performance.
InvoiceLink
Greensboro, NC
Partner: Mitch Mumma
TSX: IFM.TO
InvoiceLink is an industry knowledge leader in Web-based invoicing and payment solutions for business-to-business applications. The company was acquired by BCE Emergis in August 2000.
Jacket Micro Devices
Atlanta, GA
CEO: Jim Stratigos
Partner: John Glushik
JMD is a semiconductor packaging company that has developed a new platform technology that reduces the size and cost of the radio frequency components used in wireless devices.
KAI Pharmaceuticals
Palo Alto, CA
CEO: Stephen James
Partner: Bob Bell
KAI is developing therapeutics in the areas of acute myocardial infarction, pre-conditioning to prevent ischemic injury to the heart, neurology and transplant surgery.
LOC-AID Technologies
Boca Raton, FL
CEO: Isaias Sudit
Partner: John Glushik
LOC-AID Technologies provides location-based services aggregation for wireless users, allowing consumers to use location tracking, social networking and other applications through wireless devices.
Marathon Group
Morrisville, NC
Partner: Mitch Mumma
Nasdaq: SRNA
The Marathon Group was an Internet professional services company specializing in e-commerce solutions for clients like GlaxoSmithKline, Nike, RJR, Volvo and Wrangler. The company was acquired by MERANT in 1999, which was acquired by Serena Software in 2004.
MaxCyte, Inc.
Rockville, MD
CEO: Doug Doerfler
Partners: Chris Hegele, David Pierson
MaxCyte is a clinical stage biotechnology copmany advancing cell therapy, drug delivery and drug discovery with new cell-loading technologies.
MicroCHIPS
Bedford, MA
CEO: John Santini
Partner: Garheng Kong
MicroCHIPS designs and develops implantable silicon microchips to dispense medicine to the body or to deliver chemicals for use in diagnostics and biosensor applications.
nContact Surgical
Morrisville, NC
CEO: John Funkhouser
Partner: Dennis Dougherty
nContact Surgical is an early stage development company focused on providing new tissue coagulation devices used during surgical procedures.
Neolinear
Pittsburgh, PA
Partner: John Glushik
NYSE: CDN
Neolinear provides physical synthesis software that develops, manufactures and markets design automation systems for analog silicon design. Neolinear was acquired by Cadence Design Systems in 2004.
Nitronex
Raleigh, NC
CEO: Charlie Shalvoy
Partner: Kip Frey
Nitronex is a semiconductor company that develops advanced Gallium Nitride (GaN) materials and process technology.
NovaMin Technology
Alachua, FL
CEO: Randy Scott
Partners: Chris Hegele, Garheng Kong
NovaMin Technology, Inc. is an oral biomaterials company focused on providing tooth remineralization technology products.
nTouch Research
Raleigh, NC
CEO: Lee Palles
Partner: Mitch Mumma
nTouch is a leading provider of study management services to community physicians for Phase II-IV clinical trials services. nTouch was acquired by Accelovance in February 2005.
OpenSite Technologies
Research Triangle Park, NC
Partner: Mitch Mumma
Nasdaq: SEBL
OpenSite develops and markets web-server software to enable customers to host online auctions. The company was acquired by Siebel Systems in May 2000.
Overture Networks
Research Triangle Park, NC
CEO: Jeff Reedy
Partner: John Glushik
Overture is a supplier of carrier-class multi-service networking equipment enabling telecommunications carriers to deliver all of their services over Metro Ethernet/IP networks.
PharmaNetics
Raleigh, NC
Partner: Dennis Dougherty
Nasdaq: PHAR.PK
PharmaNetics develops and manufactures diagnostic analyzers and disposable test cards for use in cardiovascular point-of-care patient treatment.
Proteon Therapeutics
Boston, MA
CEO: Timothy Noyes
Partner: Garheng Kong
Proteon Therapeutics is a biotechnology company developing novel, first-in-class pharmaceuticals to address the critical, rapidly expanding medical needs of patients with vascular diseases.
SciQuest
Morrisville, NC
CEO: Steve Wiehe
Partner: Kip Frey
SciQuest is an e-procurement developer that offers a suite of applications initially targeted at the life sciences and higher education markets.
Semprius
Durham, NC
CEO: Joseph Carr
Partner: Kip Frey
Semprius is developing unique, patented technology that allows transfer printing of high performance semiconductors onto virtually any surface, including glass, flexible or rigid plastic, metal or other semiconductors.
Sentillion
Andover, MA
CEO: Rob Seliger
Partner: Dennis Dougherty
Sentillion develops standards-based software that enables healthcare information systems to work together.
Serenex
Durham, NC
CEO: Richard Kent
Partner: Garheng Kong
NYSE: PFE
Serenex is an oncology-focused drug development company using its novel chemoproteomics technology to accelerate the discovery of high value therapeutics for important human diseases. Pfizer announced in March 2008 it would acquire Serenex.
SmartPath
Morrisville, NC
Partners: John Glushik, Mitch Mumma
Nasdaq: DCLK
SmartPath was a leading supplier of Marketing Resource Management (MRM) solutions developed to help large companies reduce the cost and complexity of managing their marketing initiatives. SmartPath was acquired by DoubleClick in 2004.
Sphinx Pharmaceuticals
Research Triangle Park, NC
Partner: Dennis Dougherty
Nasdaq: LLY
Sphinx is dedicated to drug discovery and development by generating combinatorial libraries and high throughput screening of compounds against biological targets central to human diseases. The company went public and was subsequently acquired by Eli Lilly and Company.
SunPharm Corporation
Jacksonville, FL
Partners: Dennis Dougherty, Phil Tracy
Nasdaq: GENZ
A company engaged in the development of small molecule pharmaceutical products, consisting of novel polyamine analogues and other proprietary compounds. Acquired by public company GelTex Pharmaceuticals, which was subsequently acquired by Genzyme.
TapRoot Systems
Morrisville, NC
CEO: Bob Bicksler
Partner: Mitch Mumma
TapRoot Systems develops embedded software products for the global mobile phone marketplace, specializing in dual-mode solutions for the industry's major mobile operating systems: Microsoft Windows Mobile®, LinuxTM and Symbian®.
Trancept Systems
Raleigh, NC
Partner: Dennis Dougherty
Nasdaq: SUNW
Transcept developed a hardware accelerator for workstations speeding up mechanical engineering rendering tasks by 100x. Acquired by Sun Microsystems in 1987.
Trinity Convergence
Raleigh, NC
CEO: Ajit Pendse
Partner: Mitch Mumma
Trinity designs, develops and markets embedded communications software for telecommunications equipment manufacturers and semiconductor manufacturers.
UOL Publishing
Herndon, VA
Partner: Dennis Dougherty
Nasdaq: VCMP
UOL publishes high quality, interactive and on-demand educational courseware for the online education and training market via the web. UOL Publishing went public in 1996 and was subsequently acquired by VCampus Corporation.
Viamet Pharmaceuticals
Durham, NC
CEO: Bob Schotzinger
Partner: Garheng Kong
Viamet is a biotechnology company targeting metalloenzymes in the fields of infectious disease, inflammation and oncology.
Zenoss
Annapolis, MD
CEO: Bill Karpovich
Partner: Chris Hegele
Zenoss is an open source network and systems management software company that makes IT management available to organizations of all sizes.
Ziptronix
Morrisville, NC
CEO: Ken Donahue
Partner: Mitch Mumma
Ziptronx is a semiconductor materials processing company focused on 3-D integration of a wide variety of circuit types, including memory, processor and controller chips.
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